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KMID : 0361420100340020185
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Journal of Korean Academy of Rehabilitation Medicine
2010 Volume.34 No. 2 p.185 ~ p.188
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Short Term Effects of Transdermal Scopolamine Patch for Drooling of Saliva in Patients with Cerebral Palsy
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Roh Sung-Won
Kim Chan-Woo
Kim Tai-Kon
Lee Mun-Hwan
Lee Kyu-Hoon
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Abstract
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Objective: To investigate the clinical usefulness of the transdermal scopolamine patch applied to control drooling of saliva in patients with cerebral palsy.
Method: We enrolled twenty two patients with cerebral palsy residing in a rehabilitation center. The mean age of the patients was 24.0 years old. Transdermal scopolamine patch was applied to the patients for 2 weeks. We measured drooling quantity, severity of drooling, and visual analog scale of care givers’ labor intensity at pre-application, post 1 week, and post 2 weeks.
Results: Drooling quantity decreased significantly from 4.1 ±1.9 ml to 2.8±1.5 ml at post 1 week (p＜0.01), and 2.2±1.6 ml at post 2 weeks (p＜0.01). Severity of drooling decreased from 4.1±0.8 to 2.9±1.1 at post 2 weeks (p＜0.01). Visual analog scale of care givers’ labor intensity decreased from 78.2±17.4 (mm) to 52.7±18.6 at post 1 week (p＜0.01), and 45.9±22.8 at post 2 weeks (p＜0.01).
Conclusion: These findings suggested that the transdermal scopolamine patch is effective to reduce the drooling of saliva in patients with cerebral palsy within short term.
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KEYWORD
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Drooling, Saliva, Scopolamine patch
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